BioThrust Comfycell Incu
Key Advantages
Simple but powerful controls and convenient active aeration for fast set-up and process success
Affordable to source, fast to ship, easy to install and use, and simple to clean and maintain
Identical geometry to ComfyCell Benchtop vessels, from 300mL all the way to 200L working volume
Up to three ComfyCell Incu systems fit side-by-side in a standard cell culture incubator rack
ComfyCell Incu vs. Comparable Systems
Simple RPM controls with options for intermititent stirring automation.
Simple RPM controls with no possibility of automation.
Ease of use depends on specific vendor, may be complex or simple.
Very easy to use static system but lacks any agitation options.
Efficient process directly translates to large ComfyCell vessels up to 200L.
Process can be moved up to 80L, but process intensity drops sharply after 3L.
Scalability heavily depends on vendor and process. CGT is limited to <10L.
Cannot be scaled up, only scaled out. This increases complexity and cost.
Low shear force thanks to smooth mixing with large MemStir blades.
Low shear force thanks to smooth mixing with large vertical impeller.
Low shear force at small volume if RPM is correctly controlled.
Low shear force as static systems have basically no hydrodynamic changes.
Highly efficient active membrane aeration using incubators atmosphere.
Very low gas transfer even in small scale, limiting achievable cell densities.
Sufficient gas transfer at small scale, but higher volumes or intensity complex.
Low gas transfer due to static systems inherent surface area limitations.
Four luer ports and up to three PG 13.5 ports for cell handling and PAT.
Single port for cell handling with no convenient PAT integration.
Cell handling and PAT options heavily depend on vendor of mini STR.
Static system leave no room for online measurement or dynamic cell handling.
BioThrust ComfyCell Incu Data & Benchmarks
2.6 million iPSCs per mL in 300mL
Human uc-MSC expansion in 300mL
Neural progenitor cells on carriers in 300mL
Product Catalog & Technical Specs
| Category | Product | Part Number | Link |
|---|---|---|---|
| Control Units | ComfyCell Incu Base Unit (100-240 VAC) | int-nc-ctr-incu | |
| Single-Use Vessels | ComfyCell Incu Single-Use Vessel 300mL (Single-Cells) | int-c-isu-0.3-1 | |
| ComfyCell Incu Single-Use Vessel 300mL (Microcarriers) | int-c-isu-0.3-2 | ||
| ComfyCell Incu Single-Use Vessel 300mL (Aggregates) | int-c-isu-0.3-3 | ||
| Peripherals | ComfyCell Incu Base Unit Regional Power Cable | - | Coming Soon |
| Features | Description |
|---|---|
| Working Volume | 150 mL or 300 mL |
| Ports | 4 x Luer, 3 x PG13.5 (optional) |
| Aeration | Pump in base unit circulates incubator atmosphere through Membrane Stirrer |
| Agitation | Top-loaded direct drive |
| Standard Sensors | No inbuilt sensors |
| RPM | 0 - 150 RPM |
| Automation | Programmable intermittent stirring program available |
| Extras | LED Lights to illuminate vessel for sampling & measurement |
| Assembled Dimensions | 125 x 232 x 278 mm / 4.9 x 9.1 x 11 inch |
Process Dev. Services Available
We can develop your CGT process in-house at BioThrust or allocate dedicated 1:1 time for our bioprocess experts to work with you virtually or at your facility. From set-up to record breaking process intensification.
See How It Works
Want to see ow the ComfyCell bioreactor works? See the videos below
Download Incu Manual & Quick Start Guide
Access the Incu's documents following the links below.
